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Are boys' and girls' brains different?

The most profound difference between girls and boys is not in any brain structure per se, but rather in the sequence of development of the various brain regions. The different regions of the brain develop in a different sequence, and different tempo, in girls compared with boys.

Girls reach the inflection point (halfway in brain development) just before age 11 years; boys do not reach the inflection point until just before age 15 years.

Source: “Sexual dimorphism of brain developmental trajectories during childhood and adolescence.” Lenroot et al.