Testing for Cystic Fibrosis

There are several ways to help answer these important questions.

Genetic Carrier Testing -- More than 10 million Americans are symptomless carriers of the defective CF gene. This test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent.

Each time two carriers of the CF gene have a child, the chances are:

• 25% the child will have CF;
• 50% the child will carry the CF gene but not have CF; and
• 25% the child will not carry the gene and not have CF.

Newborn Screening -- Newborns screened for cystic fibrosis can benefit from early diagnosis and treatment, which can:

• Improve growth;
• Improve lung function;
• Reduce hospital stays; and
• Add years to life.

While newborn screening is not a definitive diagnostic test for cystic fibrosis, it may lead to tests that can rule out or confirm a CF diagnosis. The Cystic Fibrosis Foundation and the Centers for Disease Control and Prevention recommend screening for cystic fibrosis for all newborns.

Sweat Test -- If a person exhibits symptoms of CF, a doctor may order a sweat test. This simple, painless test is the best way to diagnose CF. It measures the concentration of salt in a person's sweat. A high salt level indicates CF.

Sweat tests should be done at a Cystic Fibrosis Foundation-accredited care center where strict guidelines help ensure accurate results.

For more information:

• To explore all aspects of living with CF at every stage of life, visitLIVING WITH CYSTIC FIBROSIS.
• See whatTREATMENTSare available and what's in development.