Does anyone know anything about Hyper IgE Syndrome?
My son who is 3 yrs old has Severe Eczema , Allergies and Asthma , his IgE Immuneoglobin E Level is 40,66 , he is now in a clinical trail. He has had RSV , MRSA , and other Staph infections . There is not much known about this Hyper IgE .
Hyper-IgE syndrome is an immunodeficiency syndrome characterized by chronic eczema and recurrent Staph abscesses of the skin, lungs, and joints, as well as frequent fractures. People affected by this condition may have coarse facial appearance, overly flexible joints, and abnormal teeth. First symptoms start in infancy.
hyper IgE syndrome (AD-HIES) is a rare multisystem primary immunodeficiency disorder. Symptoms often become apparent early during infancy or childhood. The disorder is characterized by repeated bacterial infections of the skin and lungs (pneumonia), skeletal abnormalities, and characteristic facial features. The first symptom is often the development of a dry, red flaky skin rash (eczema) at birth or early during infancy.