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Director's Choice Science Fair Project Ideas (page 3)

By Brady Gentry, Director, Louisiana Region 5 Science and Engineering Fair
Louisiana Region 5 Science and Engineering Fair

Medicine and Health

  1. Medicine & Health - Also from the December 2003 issue of Discover, an article entitled - Forecast: A Chilly Scorcher - How Your Body Mistakes A Cold Front For a Heat Wave. Experment 1: Find two glasses and three identical knives with metal handles. Fill one glass with cold water and ice cubes, and place one of the knives, handle first, into it. Next, fill the other glass with tap water that is very warm but not painfully hot. Then dunk the remaining two knife handles into the heated water for 60 seconds. Ask a friend to extract the knives, fit the cold handle snugly between the two warm ones, and then quickly touch the three handles to the inside of your wrist as you close your eyes. You'll experience a burning sensation that is more intense than what would be evoked by placing the two warm handles on the same spot. The sensory confusion, which neurologists call the thermal-grill illusion, may occur because cold objects touching the skin simultaneously stimulate both fast-conducting (A-delta type) nerve fibers that signal cold and slower (C-type) fibers that signal pain. Fast and slow sensory nerves connect to a single place in the spinal cord, and that pain information is then passed on to the brain. Signals from the faster, cold-transmitting fibers inhibit those spinal relays from the slower, pain-transmitting fibers. The net result is that cold stimulus elicits cold but not pain sensations , even though some pain fibers are initially turned on. However, two warm stimuli placed right next to a cold object can dilute the amount of cold information flowing from a patch of skin. In Experiment 2 - The dilution of a cold stimulus by a warm one implies that the different signals are blended over a broad patch of akin - a phenomenon known as spatial summation. Repeat Experiment 1, but this time ask your accomplice to place the handles on your lips. You should perceive a three-part warm-cold-warm sensation (with no pain). That is because your lips do not lump together tactile inputs from broad swaths of skin and so can discern much finer details. Neurologists study temperature-pain illusions because about 3 million Americans who have nerve damage from diabetes or trauma experience a disorder called neuropathic pain. For these individuals, even a light touch or a cool breeze can produce extremely painful, burning sensations. Research thermal-grill illusion and spatial summation. Get some test groups - females, males - young and old. Does the summation subside with age or physical condition? See if other parts of the body are affected in the same way or not.
  2. Medicine & Health - One of the more interesting projects that I like deals with testing subject's sense of taste. My daughter did a project some years back that involved testing her subject's tongues with sweet, sour, bitter, and salty solutions. She broke the result down based on gender, age, and smoking - nonsmoking. (A lot of photos and a lot of charts and graphs) She placed second in State competition. It was after the project that I learned about a 5th taste - Umami. (Go to following link to get initial information on this - http://www.abc.net.au/science/news/stories/s95290.htm ) Had she known about these mysterious receptors, my daughter would have included it in her experiment. After reading more about Umami, I am beginning to believe this has something to do with my great love for Chinese food. I would suggest doing a project that includes the four senses, plus the 5th sense - Umami. Another part of this project could include some research on the palate. Taste buds are not only located on the tongue. They are also found on the human palate. I have noticed that in recent years, the taste buds on my palate have become extremely susceptible to the different tastes, even more so than the ones on my tongue. Could it be that as a person gets older, most of the tasting occurs on the palate vs. the tongue, or is there something else going on? We emailed Dr. Linda Bartoshuk, one of the world's foremost experts in the study of taste and the senses. Following was her reply: It is hard to find information about the pallet. It might help for you to have the name of the nerve that carries taste information from the pallet to the brain. It is the greater superficial petrosal nerve. If you look up that nerve, you will find information about taste. There is information about taste on the pallet in other species and in humans. We do measures of taste on the pallet routinely in the laboratory. You might be interested to know that the tongue map in so many text books is wrong. The maps suggest that the front of the tongue tastes sweet, the back, bitter and the sides, salty and sour. Actually, this is based on a mistranslation of a German article. I love to tell people this because I am at Yale and the professor who mistranslated the article was at Harvard! Wherever there are taste buds, we taste all four tastes: sweet, salty, sour bitter. The goes for the pallet as well. Working with, or incorporating Umami and the palate would bring the taste testing project into a whole new and unique area. If you end up wanting to tackle something like this and would like some more pointers on how to make this a successful project, them email me and let me know.
  3. Medicine & Health - This may seem like a "gross" idea for a project, but I did not find there has been that much research done on this. You may have heard the tale that "asparagus urine" is linked to higher intelligence. The fact is that it is the result of a simple chemical reaction. Asparagus contains a sulfur compound called mercaptan. Mercaptan is a sulfur-containing organic compound with the general formula RSh, where R is any radical, especially ethyl mercaptan, C2 H5SH. It is also called thiol. When your digestive tract breaks down this substance, by-products are released that cause the odd scent in your urine. The process is so quick that your urine can develop the distinctive smell within 15 to 30 minutes. But not everyone has this experience. Your genetic makeup may determine whether your urine has the odor - or whether you can actually smell it. Only some people appear to have the gene for the enzyme that breaks down mercaptan into its more pungent parts. I read that a study published in the May 1989 British Journal of Clinical Pharmacology found that 46% of 115 people tested produced the odor in one group of British citizens, while 100% of 103 people produced it in a group of French citizens. Another study found that 10% of a group of 300 Israeli Jews could not detect the odor. This may all sound scary, but it is not bad. On the contrary, asparagus is s powerhouse of nutrients. Here is where the research and experimentation would come into play. This bit of research that I located points only to nationality. I would suggest doing testing on males vs. females, different age groups, smokers vs. non-smokers, different nationalities, average weight vs. overweight, etc. Try to establish a pattern. Try to identify which types of people have a genetic makeup that allows the mercaptan to break down at these accelerated rates. One benefit is this could lead to research that would lead to developing medicine that would get into a person's system faster. This is a project that has a lot of potential. Generate a question form for the test subject and supply them with some asparagus. Have them return only the questionnaire to you.
  4. Medicine & Health - The following is another article written by Alison McCook. NEW YORK (Reuters Health) - Skipping a meal or two makes you more sensitive to the taste of your next sweet or salty snack, new research shows. After a group of people went for about 15 hours without eating, they became better able to taste the miniscule amounts of sweet or salty flavors added to solutions, compared to when they tasted the same solutions on a full stomach. In contrast, hunger had no influence on participants' abilities to detect bitter tastes, the report indicates. "We have discovered that hunger increases sensitivity of taste to sweet and salty substances but it does not affect taste sensitivity to bitter substances," study author Dr. Yuriy Zverev told Reuters Health. Zverev added that hungry people's taste buds may respond differently to salt, sweet and bitter because those tastes communicate different things about our food. Sweet and salty tastes are often signs that a particular food is edible, he explained, so when we are hungry, our bodies become more sensitive to what foods can fill our stomachs. Once we are full, however, it is less important for us to be tuned into food, and we may consequently lose our sensitivity to the taste cues of what makes something edible. As he put it, "Biological significance of substances of nutritional value declines after a meal." In contrast, a bitter tastes signals that the food is "not suitable for consumption and should be rejected," Zverev noted, and this is an important message to heed, regardless of whether or not we are hungry. During the study, Zverev, who is based at the University of Malawi, asked 16 non-obese men to taste a number of substances that contained different concentrations of sweet, salty and bitter flavors. He measured the least amount of flavor needed for participants to correctly identify the taste when they were not hungry, and compared that to least flavored solution they could taste when hungry. During periods of hunger, people could taste the sweet and salty flavors added to solutions that they rated as tasteless when well-fed, Zverev reports in the journal BMC Neuroscience. Although the bodily processes that enable tasters to change their sensitivity to flavors when hungry are not clear, Zverev suggested that periods of hunger may result in changes in the taste buds themselves or the regions of the brain that process taste. SOURCE: BMC Neuroscience 2004
  5. Medicine & Health - As I was running an errand the other day, I passed under a run of high-voltage power lines. (The passed over the roadway) This brought to mind past and current concerns by folks that living under or near high-voltage lines, and EMF's, can cause negative physiological effects on the human body. I know there have been studies done on trying to tie in certain types of cancer and increased health symptoms with high-voltage equipment. The latest information that I can find indicates that results of studies are not definitive. What did come to mind was this. If you are able to legally and safely access the area underneath high-voltage lines then try doing a research project that determined if underground life directly under the lines was less abundant than the same type of life 200 feet away. I would suggest taking soil samples of various depths and distances in parallel with the lines. See what type of animal or insect life is present. Log down the type of size of what you found along with the depth and locations. ( x inches, x feet from the tower, earthworms averaging 5 inches in length and 1/8 inch diameter, and any other forms of life that reside in the soil). Then proceed out 200 feet away and repeat the process covering the same distance and depth. One thing you would want to try to make sure is that the soil type and consistency was as much the same as possible. Also, if you can get access to a EMF meter to take readings, that would be a plus. You might try contacting an electrical contractor or the science department of a local college or university. I did a quick search on the Internet for any type of studies similar to this idea and have discovered none. Who knows, you might discover something that no one else has.
  6. Medicine & Health - A while back I read an article about shops in Europe that would play a high frequency sound, that only young people could hear, to keep them from loitering outside their place of business. This sound is apparently in the 17 khz range. As people grow older, they loose the ability to hear sounds in the high frequency range. Well, we all know that teens are not only smart, they are very innovative. The younger generation seized upon this sound and turned it into a ringtone. Eureka! Their cell phone can ring in class without the teacher hearing it. I have tried this ringtone on co-workers and the only one that can hear it is someone in their late 20's. A good experiment would be to test many different age groups - both male and female - to see where the break point is for this sound. (at least 100 test subjects would be needed to give good results) A good testing time of day would be in the morning and a quite location would be needed. If by chance you run across someone old like me that can hear this "mystery sound", then try to get as much health information as possible. (type of work they do, if they have ever been exposed to loud noises, etc). You may find that one gender looses that ability to hear in the high frequency range before the other. I don't know but you may also discover that a human doesn't develop the ability to hear this sound until a certain age. (which would mean that you would have to test pre-schoolers). And then why stop at humans - extend the experimentation to animals (dogs, cats, etc.). You might discover that this sound keeps away certain nuisance animals away from your home. I have included download links below for this sound - both in MP3 and Wav format. MP3 is of lower quality than wav. If you use your cell phone for producing the sound, remember that it may not be able to generate a sound in the 17 khz range. Using a iPod or portable MP3 player would work. This would be a very unique project and sure to win prizes if done thoroughly and with many test subjects. (MP3) (WAV)
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