Mad Cow Disease

Mad Cow Disease
photo by: rolands.lakis
The Nemours Foundation

About Mad Cow Disease

Mad cow disease has been in the headlines in recent years. While a serious illness, it primarily affects cattle and, possibly, other animals, like goats and sheep. The medical name for mad cow disease is bovine spongiform encephalopathy, or BSE for short.

BSE is an incurable fatal brain disease. It is called mad cow disease because it affects a cow's nervous system, causing the animal to act strangely and lose control of its ability to do normal things, such as walk.

Only certain animals can get BSE — people don't actually get mad cow disease. However, experts have found a link between BSE and a rare brain condition that affects people called variant Creutzfeldt-Jakob disease (vCJD). Researchers believe that people who eat products from cows that have BSE are at risk of developing vCJD.

vCJD is caused by an abnormal type of protein in the brain called a prion. When people have vCJD, cells in the brain die until the brain eventually has a "sponge-like" appearance. During this time, people with the disease gradually lose control of their mental and physical capabilities.

To date, very few people have been diagnosed with the form of vCJD. By October 2009, only 217 cases of this rare condition had been reported worldwide. Of these, most were identified in Britain. Several of the people diagnosed with the disease outside Britain — including two cases in the United States — had a history of exposure in Britain.

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